Seinfeldhas introduced the world to some of the wackiest TV characters in sitcom history, with its eclectic cast helping to make it one of the greatest comedy series of all time. The cameos and small appearances by other actors became a staple of the series as a whole, with the main cast of Elaine, George, Kramer, and Jerry having to deal with all the mundane issues they bring into their lives.
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The show has helped propel the acting careers of many previously unknown celebrities and featured well-established actors to show off their talents.
Jennifer Coolidge
The actress starred as one of Jerry’s many girlfriends on the show, who refused to give Jerry a massage even though she worked as a massage therapist. Her romantic stint with the stand-up comedian didn’t last long, unsurprisingly, with Jerry breaking up with her by the episode’s end. She looks almost unrecognizable without her signature bleach-blonde hair, but she still looks fabulous.
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Since being onSeinfeld,Jennifer Coolidgehas made a name for herself through her work onBest in Show, A Cinderella Story, American Pie,andLegally Blonde,which has established her talent as a comedy powerhouse. She has also reached critical acclaim for her recent role in the HBO limited series,The White Lotus.
Sarah Silverman
Sarah Silvermanstarred inSeinfeldas Kramer’s girlfriend and has “jimmy legs,” meaning that she kept twitching her legs uncontrollably while sleeping, keeping Kramer up at night.
Behind the scenes, Sarah andMichael Richardsdid not get along when they rehearsed lines, with Silverman revealing that Richardsyelled at her when she accidentally messed up a line. They ended their work together on friendly terms, however.

Patton Oswalt
Patton Oswaltworked as a video store clerk in the show as his first ever paid acting gig back in 1994. From his appearance onSeinfeld,he would gain further notice through his role inThe King of Queens.
Patton also ventured into voice work and starred inPixar’sRatatouille,as well as making various other roles in shows such asParks and Recreation,Community,andVeep,as well as more recently starring in theNetflixadaptation ofNeil Gaiman’sThe Sandman.

Bryan Cranston
Before he landed the role as Hal onMalcolm in the Middle, and way before his career-defining work onBreaking Badas Walter White,Bryan Cranstonhad a role onSeinfeldas Jerry’s dentist, Tim Whatley.
Tim was one ofSeinfeld’skookiest characters, partaking in many antics that annoyed Jerry, such as being a serial “re-gifter” and converting to Judaism so he could make Jewish jokes. Cranston’s work in Seinfeld helped show off his excellent comedic skills, leading to his more well-known acting feats.

Courteney Cox
Achieving the almost impossible task of landing a role in not one buttwoof the most iconic New York-based sitcoms from the ’90s is incredibly impressive forCourteney Cox, who is, of course, most well-known for her work onFriendsas Monica.
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Cox only appeared inSeinfeldfor one episode as, you guessed it, one of Jerry’s girlfriends, who refers to herself as Jerry’s “wife,” to take advantage of Jerry’s discount at the dry cleaning. They, of course, break up by the end of the episode, with Jerry “cheating” on her by letting another woman use the discount.
Bob Odenkirk
AnotherBreaking Badalum,Bob Odenkirk,appeared on the classic show about nothing as one of Elaine’s boyfriends. Odenkirk was already acting on other shows at the time, such as the cult sketch-comedy showMr. Show with Bob and DavidalongsideDavid Cross, which featured the talents of Sarah Silverman andJack Black.
He would then reach fame with his role as Saul Goodman onBreaking Bad, leading to the prequel series about his life,Better Call Saul.

Debra Messing
Although she would go on to fame with her breakthrough role as Grace on anotherNBCsitcom,Will and Grace,Debra Messingwas a minor character in Seinfeld called Beth Lookner.
She worked as a physician on the show and held a perceived prejudice against dentists, which was later revealed to be true with her also holding pretty strong anti-Semitic and racist beliefs as well. Jerry then, of course, dumped her, marking this as her final appearance on the show.